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1

Synthesis and glycosidase inhibitory activities of 2-(aminoalkyl)pyrrolidine-3,4-diol derivatives

Ana T Carmona, Florence Popowycz, Sandrine Gerber-Lemaire, Eliazar Rodrı́guez-Garcı́a, Catherine Schütz, Pierre Vogel, Inmaculada Robina

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 464 KB

english, 2003

2

Reduction of aromatic and aliphatic nitro groups to anilines and amines with hypophosphites associated with Pd/C

Baron, Marc, Métay, Estelle, Lemaire, Marc, Popowycz, Florence

Journal:

Green Chemistry

Year:

2013

Language:

english

File:

PDF, 462 KB

english, 2013

3

One-Pot, Solvent-Free Access to Unsymmetrical Ureas by Palladium-Catalysed Reductive Alkylation Using Molecular Hydrogen

Mohy El Dine, Tharwat, Chapron, Simon, Duclos, Marie-Christine, Duguet, Nicolas, Popowycz, Florence, Lemaire, Marc

Journal:

European Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 739 KB

english, 2013

4

The Piancatelli Reaction and its Variants: Recent Applications to High Added-Value Chemicals and Biomass Valorization

Verrier, Charlie, Moebs-Sanchez, Sylvie, Queneau, Yves, Popowycz, Florence

Journal:

Organic & Biomolecular Chemistry

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

5

Harnessing cascade Suzuki-cyclization reactions of pyrazolo[3,4-b]pyridine for the synthesis of tetracyclic fused heteroaromatics

Lavrard, Hubert, Popowycz, Florence

Journal:

European Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.68 MB

english, 2016

6

C2 Arylated Benzo[ b ]thiophene Derivatives as Staphylococcus aureus NorA Efflux Pump Inhibitors

Liger, François, Bouhours, Pascale, Ganem-Elbaz, Carine, Jolivalt, Claude, Pellet-Rostaing, Stéphane, Popowycz, Florence, Paris, Jean-Marc, Lemaire, Marc

Journal:

Year:

2016

Language:

english

File:

PDF, 661 KB

english, 2016

7

ChemInform Abstract: Direct Arylation: Alternative to Classic Cross-Coupling Chemistry and a Fruitful Synthetic Tool for the Access to Novative Bioactive Molecules

Florence Popowycz, Estelle Metay, Marc Lemaire

Journal:

Year:

2011

File:

PDF, 18 KB

2011

8

Structure−Activity Relationship and Multidrug Resistance Study of New S -trityl- l -Cysteine Derivatives As Inhibitors of Eg5

Kaan, Hung Yi Kristal, Weiss, Johanna, Menger, Dominik, Ulaganathan, Venkatasubramanian, Tkocz, Katarzyna, Laggner, Christian, Popowycz, Florence, Joseph, Benoît, Kozielski, Frank

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.43 MB

english, 2011

9

The synthesis of HMF-based α-amino phosphonates via one-pot Kabachnik–Fields reaction

Fan, Weigang, Queneau, Yves, Popowycz, Florence

Journal:

Year:

2018

Language:

english

File:

PDF, 580 KB

english, 2018

10

Direct amination of isohexides via borrowing hydrogen methodology: regio- and stereoselective issues

Bahé, Florian, Grand, Lucie, Cartier, Elise, Jacolot, Maiwenn, Moebs-Sanchez, Sylvie, Portinha, Daniel, Fleury, Etienne, Popowycz, Florence

Journal:

European Journal of Organic Chemistry

Year:

2019

File:

PDF, 2.23 MB

2019

11

Indolobenzazepin-7-ones and 6-, 8-, and 9-Membered Ring Derivatives as Tubulin Polymerization Inhibitors: Synthesis and Structure−Activity Relationship Studies

Putey, Aurélien, Popowycz, Florence, Do, Quoc-Tuan, Bernard, Philippe, Talapatra, Sandeep K., Kozielski, Frank, Galmarini, Carlos M., Joseph, Benoît

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.25 MB

english, 2009

12

Efficient C-3 reductive alkylation of 4-hydroxycoumarin by dehydrogenative oxidation of benzylic alcohols through ruthenium catalysis

Montagut-Romans, A., Boulven, M., Lemaire, M., . Popowycz, F

Journal:

New Journal of Chemistry

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

13

ChemInform Abstract: Commutative Reduction of Aromatic Ketones to Arylmethylenes/Alcohols by Hypophosphites Catalyzed by Pd/C under Biphasic Conditions.

Guyon, Carole, Baron, Marc, Lemaire, Marc, Popowycz, Florence, Metay, Estelle

Journal:

Year:

2014

File:

PDF, 27 KB

2014

14

ChemInform Abstract: An Efficient Combinatorial Method for the Discovery of Glycosidase Inhibitors.

Sandrine Gerber-Lemaire, Florence Popowycz, Eliazar Rodriguez-Garcia, Ana Teresa Carmona Asenjo, Inmaculada Robina, Pierre Vogel

Journal:

Year:

2002

File:

PDF, 24 KB

2002

15

Commutative reduction of aromatic ketones to arylmethylenes/alcohols by hypophosphites catalyzed by Pd/C under biphasic conditions

Guyon, Carole, Baron, Marc, Lemaire, Marc, Popowycz, Florence, Métay, Estelle

Journal:

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

16

Cytotoxic Nucleoside Analogues: Different Strategies to Improve their Clinical Efficacy

Galmarini, C., Popowycz, F., Joseph, B.

Journal:

Current Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 277 KB

english, 2008

17

New insights into catalytic reduction of aliphatic nitro compounds with hypophosphites under ultrasonic irradiation

Letort, Sophie, Lejeune, Manuel, Kardos, Nathalie, Metay, Estelle, Popowycz, Florence, Lemaire, Marc, Draye, Micheline

Journal:

Green Chemistry

Year:

2017

Language:

english

File:

PDF, 860 KB

english, 2017

18

Enantioselective straightforward access to benzo[b]thiophene analogs of Azatoxin

Stéphanie Gracia, Cédric Marion, Jullien Rey, Florence Popowycz, Stéphane Pellet-Rostaing, Marc Lemaire

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

19

ChemInform Abstract: Enantioselective Straightforward Access to Benzo[b]thiophene Analogues of Azatoxin.

Stephanie Gracia, Cedric Marion, Jullien Rey, Florence Popowycz, Stephane Pellet-Rostaing, Marc Lemaire

Journal:

Year:

2012

File:

PDF, 36 KB

2012

20

Asymmetric Synthesis of 1-Aminopentadecane-3,5,7,9,11,13,15-heptols and of 1,15-Diaminopentadecane-3,5,7,9,11,13-hexols and Derivatives

Gerber-Lemaire, Sandrine, Popowycz, Florence, Glanzmann, Cécile, Vogel, Pierre

Journal:

Year:

2002

Language:

english

File:

PDF, 318 KB

english, 2002

21

Solvent-Free Michael Addition to Non-protected 3-(2-Nitrovinyl)indole by Ultrasound Activation

Baron, Marc, Métay, Estelle, Lemaire, Marc, Popowycz, Florence

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 296 KB

english, 2012

22

Straightforward Synthesis of 2-Acetyl-Substituted Benzo[b]thiophenes

Debray, Julien, Lemaire, Marc, Popowycz, Florence

Journal:

Year:

2012

Language:

english

File:

PDF, 192 KB

english, 2012

23

ChemInform Abstract: Reduction of Aromatic and Aliphatic Nitro Groups to Anilines and Amines with Hypophosphites Associated with Pd/C.

Baron, Marc, Metay, Estelle, Lemaire, Marc, Popowycz, Florence

Journal:

Year:

2013

File:

PDF, 28 KB

2013

24

Novel non-toxic and non-hazardous solvent systems for the chemistry of indoles: use of a sulfone-containing Brønsted acid ionic liquid catalyst in butyl acetate

El-Harairy, Ahmed, -, Yiliqi, Yue, Meie, Fan, Weigang, Popowycz, Florence, Queneau, Yves, Li, Minghao, Gu, Yanlong

Journal:

Year:

2019

Language:

english

File:

PDF, 4.08 MB

english, 2019

25

Synthetic applications of hypophosphite derivatives in reduction

Guyon, Carole, Métay, Estelle, Popowycz, Florence, Lemaire, Marc

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

26

A Non-Classical Route to 2,3-Diiodoindoles from Indole-2-carboxylic Acids

Putey, Aurélien, Popowycz, Florence, Joseph, Benoît

Journal:

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

27

Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase: effects on cell toxicity and osteoblast-induced mineralization

Marquès, Stéphanie, Buchet, René, Popowycz, Florence, Lemaire, Marc, Mebarek, Saïda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 789 KB

english, 2016

28

Functionalized Pyrrolidines Inhibit α-Mannosidase Activity and Growth of Human Glioblastoma and Melanoma Cells

Fiaux, Hélène, Popowycz, Florence, Favre, Sylvain, Schütz, Catherine, Vogel, Pierre, Gerber-Lemaire, Sandrine, Juillerat-Jeanneret, Lucienne

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 299 KB

english, 2005

29

Bio-Based Amides from Renewable Isosorbide by a Direct and Atom-Economic Boric Acid Amidation Methodology

Janvier, Marine, Moebs-Sanchez, Sylvie, Popowycz, Florence

Journal:

European Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

30

A continuous spectrophotometric assay that distinguishes between phospholipase A1 and A2 activities

El Alaoui, Meddy, Soulère, Laurent, Noiriel, Alexandre, Popowycz, Florence, Khatib, Abdallah, Queneau, Yves, Abousalham, Abdelkarim

Journal:

The Journal of Lipid Research

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

31

Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum

Damin-Pernik, M., Espana, B., Besse, S., Fourel, I., Caruel, H., Popowycz, F., Benoit, E., Lattard, V.

Journal:

Drug Metabolism and Disposition

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

32

Superacidic Cyclization of Activated Anthranilonitriles into 2-Unsubstituted-4-aminoquinolines

Lavrard, Hubert, Larini, Paolo, Popowycz, Florence

Journal:

Organic Letters

Year:

2017

Language:

english

File:

PDF, 974 KB

english, 2017

33

Synthesis and reactivity of 4-, 5- and 6-azaindoles

Florence Popowycz, Jean-Yves Mérour, Benoît Joseph

Journal:

Year:

2007

Language:

english

File:

PDF, 1.51 MB

english, 2007

34

Straightforward synthesis of indolizidine alkaloid 167B

Stéphanie Gracia, Rudolf Jerpan, Stéphane Pellet-Rostaing, Florence Popowycz, Marc Lemaire

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 421 KB

english, 2010

35

Synthesis and evaluation of P-chirogenic monodentate binaphthyl phosphines

Duclos, Marie-Christine, Singjunla, Yuttapong, Petit, Christelle, Favre-Réguillon, Alain, Jeanneau, Erwann, Popowycz, Florence, Métay, Estelle, Lemaire, Marc

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 491 KB

english, 2012

36

Enantioselective rhodium-catalyzed hydroacylation to access the four stereoisomers of anti-rodent difenacoum

Jacolot, Maïwenn, Moebs-Sanchez, Sylvie, Popowycz, Florence

Journal:

Tetrahedron Letters

Year:

2017

Language:

english

File:

PDF, 341 KB

english, 2017

37

Access to Paullone Analogues by Intramolecular Heck Reaction

Lionel Joucla, Florence Popowycz, Olivier Lozach, Laurent Meijer, Benoît Joseph

Journal:

Helvetica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 140 KB

english, 2007

38

Electroencephalographic Observations In Patients With Chronic Obstructive Lung Disease (Cold) Treated With AlmitriNe, A New Respiratory Analeptic Agent

Verstraeten, J.M., Popowycz, W., Vander, Eecken H.

Journal:

Acta Clinica Belgica

Year:

1980

Language:

english

File:

PDF, 2.50 MB

english, 1980

39

Bromination of 3-substituted benzo[b]thiophenes: access to Raloxifen intermediate

François Liger, Stéphane Pellet-Rostaing, Florence Popowycz, Marc Lemaire

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 514 KB

english, 2011

40

Derivatives of (2R,3R,4S)-2-Aminomethylpyrrolidine-3,4-diol are selective α-Mannosidase inhibitors

Florence Popowycz, Sandrine Gerber-Lemaire, Raynald Demange, Eliazar Rodriguez-Garcı́a, Ana Teresa Carmona Asenjo, Inmaculada Robina, Pierre Vogel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

41

PGF 2α modulates the output of chemokines and pro-inflammatory cytokines in myometrial cells from term pregnant women through divergent signaling pathways

Xu, Chen, Liu, Weina, You, Xingji, Leimert, Kelycia, Popowycz, Krystyn, Fang, Xin, Wood, Stephen L., Slater, Donna M., Sun, Qianqian, Gu, Hang, Olson, David M., Ni, Xin

Journal:

Molecular Human Reproduction

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

42

3-Methylene-2,4-chromandione in situ trapping : Introducing molecular diversity on 4-hydroxycoumarin

Montagut-Romans, Adrien, Boulven, Manon, Lemaire, Marc, Popowycz, Florence

Journal:

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

43

ChemInform Abstract: One-Pot, Solvent-Free Access to Unsymmetrical Ureas by Palladium-Catalyzed Reductive Alkylation Using Molecular Hydrogen.

El Dine, Tharwat Mohy, Chapron, Simon, Duclos, Marie-Christine, Duguet, Nicolas, Popowycz, Florence, Lemaire, Marc

Journal:

Year:

2014

File:

PDF, 30 KB

2014

44

Pyrazolo[1,5- a ]-1,3,5-triazine as a Purine Bioisostere: Access to Potent Cyclin-Dependent Kinase Inhibitor ( R )-Roscovitine Analogue

Popowycz, Florence, Fournet, Guy, Schneider, Cédric, Bettayeb, Karima, Ferandin, Yoan, Lamigeon, Cyrile, Tirado, Oscar M., Mateo-Lozano, Silvia, Notario, Vicente, Colas, Pierre, Bernard, Philippe, Me

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 162 KB

english, 2009

45

Nitrogen-functionalized Isohexides in Asymmetric Induction

Janvier, Marine, Moebs-Sanchez, Sylvie, Popowycz, Florence

Journal:

CHIMIA International Journal for Chemistry

Year:

2016

Language:

english

File:

PDF, 347 KB

english, 2016

46

Synthesis and α-Mannosidase Inhibitory Evaluation of (2R,3R,4S)- and (2S,3R,4S)-2-(Aminomethyl)pyrrolidine-3,4-diol Derivatives

Florence Popowycz, Sandrine Gerber-Lemaire, Eliazar Rodriguez-García, Catherine Schütz, Pierre Vogel

Journal:

Helvetica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 485 KB

english, 2003

47

ChemInform Abstract: Nitrogen-Functionalized Isohexides in Asymmetric Induction

Janvier, Marine, Moebs-Sanchez, Sylvie, Popowycz, Florence

Journal:

Year:

2016

File:

PDF, 14 KB

2016

48

Syntheses and Glycosidase Inhibitory Activities of 2-(Aminomethyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol Derivatives

Florence Popowycz, Sandrine Gerber-Lemaire, Catherine Schütz, Pierre Vogel

Journal:

Helvetica Chimica Acta

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

49

Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives

Florence Popowycz, Cédric Schneider, Salvatore DeBonis, Dimitrios A. Skoufias, Frank Kozielski, Carlos M. Galmarini, Benoît Joseph

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 586 KB

english, 2009

50

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine

Bettayeb, K., Sallam, H., Ferandin, Y., Popowycz, F., Fournet, G., Hassan, M., Echalier, A., Bernard, P., Endicott, J., Joseph, B., Meijer, L.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 1000 KB

english, 2008

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